Isolated Adrenocorticotropic Hormone Deficiency (ACTH) Associated with Hashimoto’s Disease

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Isolated Adrenocorticotropic Hormone (acth) Deficiency Associated with Hashimoto's Disease

Isolated ACTH deficiency (IAD) is a rare disease which is characterized by secondary adrenal insufficiency with low cortisol production and normal secretion of pituitary hormones other than ACTH. Isolated ACTH deficiency has rare association with Hashimoto’s disease which is characterized by autoimmune origin. This suggests the possibility of common autoimmune process affecting both the pituita...

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[A case of isolated adrenocorticotropic hormone (ACTH) deficiency associated with severe hyponatremia and an empty sella].

概要 症例 は56才,男 性.54才 時 よ り食欲不 振が 出現,昭 和59年,低Na血 症 にて入院.昭 和60 年4月 よ り悪 心,嘔 吐 出現 し当科 紹介.血 清Naの 最低値は105mEq/1.血 中コ ルチ ゾール,尿 中17-OHCSの 著 しい基 礎低値.血 漿ACTH基 礎 値 は測定 感度 以下 で,イ ンス リン低 血糖, L8-V,CRFに 無反 応.他 の下垂体前 葉ホル モ ン正常.ACTH単 独 欠損症 と診 断,画 像診 断上empty sellaが確認 された.低Na血 症下 のACTH-Z負 荷 にてコルチ ゾール,17-OHCSLは 増加 し,自 由 水 ク リア ラ ンス は一0.85~ 一0.95m1/分 よ りほぼ0に 至 り,低Na血 症 は改善, ADHは1.4→0.5 pg/mlと 低下 した.本 例 の低Na血 症 に はグルコ...

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Isolated adrenocorticotrophic hormone (ACTH) deficiency associated with acute adrenal crisis.

A 37 year old black female presented with congestive cardiac failure, 2 months postpartum. She developed spontaneous hypoglycaemia and symptoms of acute adrenal crisis (hypotension, nausea, abdominal pain and tachycardia with small thready pulse), which responded to i.v. dextrose, sodium chloride and hydrocortisone. Biochemical investigations revealed low serum cortisol and plasma adrenocortico...

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Thyroid dysfunction in isolated adrenocorticotropic hormone (ACTH) deficiency: case report and literature review.

A case of isolated ACTH deficiency accompanying transient primary hypothyroidism was reported along with a review of literature on isolated ACTH deficiency in Japan with special reference to its association with thyroid function. Our case, a 56-year-old woman, developed somnolence and hypoglycemia due to isolated ACTH deficiency. She also had the features of hypothyroidism, namely mounding phen...

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Petrified Ear Auricles with Isolated Adrenocorticotropic Hormone Deficiency

A 22-year-old man was hospitalized with nausea. His serum sodium, adrenocorticotropic hormone (ACTH), and cortisol levels were 108 mmol/L (range, 138-145), 2.2 pg/mL (range, 7.2-63.3), and 0.08 μg/dL (range, 4.64-24.56), respectively. The levels of other anterior pituitary hormones were as follows: growth hormone 2.46 ng/mL (range, 0.663.68), thyroid-stimulating hormone 0.625 μIU/mL (range, 0.5...

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ژورنال

عنوان ژورنال: Turkish Journal of Endocrinology and Metabolism

سال: 2014

ISSN: 1301-2193

DOI: 10.4274/tjem.2341